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Sensitivity of ACT-451840-resistant lines to clinical antimalarials. Susceptibility of parental and mutant lines to (A) mefloquine, (B) lumefantrine, and (C) quinine. Bar graphs display mean IC50 values ± S.E.M. Student’s t-test was performed comparing resistant to parental lines. *P < 0.05, **P < 0.005.
