Table 3.
Associations of changes LVEF and CMR characteristic with appropriate shock and HF hospitalization
| Appropriate shock (n=23) | Heart failure hospitalization (n=45) | |||
|---|---|---|---|---|
| Model 1 * | Model 2 † | Model 1 * | Model 2 † | |
| HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| Changes in LVEF | ||||
| Worsened | 1.09(0.38, 3.10) | 1.16(0.39, 3.45) | 2.78(1.34, 5.79) | 2.88(1.33, 6.25) |
| Unchanged | Reference | Reference | Reference | Reference |
| Improved | 0.39(0.13, 1.23) | 0.50(0.16, 1.59) | 0.39(0.18, 0.84) | 0.37(0.17, 0.82) |
| P-trend | 0.08 | 0.17 | <0.001 | <0.001 |
| CMR scar variable ‡ | ||||
| Etiology-specific tertile 1 | Reference | Reference | Reference | Reference |
| Etiology-specific tertile 2 | 1.86(0.59, 5.88) | 1.69(0.55, 5.21) | 1.36(0.64, 2.90) | 1.27(0.56, 2.89) |
| Etiology-specific tertile 3 | 2.89 (0.92, 9.10) | 2.39 (0.79, 7.24) | 1.26 (0.54, 2.91) | 0.88 (0.37, 2.11) |
| P-trend | 0.07 | 0.12 | 0.55 | 0.82 |
Model 1: Adjusted for age, sex, race, device type, atrial fibrillation, cardiomyopathy etiology, and baseline LVEF.
Model 2: Further included changes in LVEF and CMR scar variable in the same model.
This variable represents gray zone among participants with ischemic cardiomyopathy and total scar among participants with non-ischemic cardiomyopathy, respectively