. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: Cancer Causes Control. 2016 Jul 5;27(8):1043–1047. doi: 10.1007/s10552-016-0782-x

Table 2.

Relative risk of prostate cancer mortality by combined vessel morphology score among 234 patients with Gleason score 7 (4+3) and 8+

	Group 1: less angiogenic	Combined morphology score^a Group 2: moderately angiogenic	Group 3: more angiogenic
Events/n	7/67	10/79	35/88
Follow-up time, py	9,921	12,995	13,286
Model 1 HR (95% CI)	1.00	1.03 (0.39, 2.70)	3.42 (1.51, 7.76)
Model 2 HR (95% CI)^b	1.00	1.04 (0.39, 2.76)	3.32 (1.45, 7.60)

Abbreviation: py, person years; HR, hazard ratio; CI, confidence interval.

We categorized vessel irregularity and vessel area into two groups according to the median values. Men were categorized into the more angiogenic group if they had both more irregular vessel lumen and smaller vessel area; men were categorized into the less angiogenic group if they had both less irregular vessel lumen and larger vessel area. The rest of men were grouped into the moderately angiogenic group.

Cox proportional hazards regression model adjusted for age at diagnosis (years, continuous), body mass index at diagnosis (kg/m², continuous), smoking status at diagnosis (never, past, current), and vigorous exercise at diagnosis (hr/week, continuous).