Table 3.
Proportion of Universal Data Collection program enrollees reporting an invasive orthopedic intervention (IOI) in the starting and ending years of the study, along with the statistical significance of the trend test.
| Percentage of IOI in 2000 | Percentage of IOI in 2010 | Minimum percentage value (Year) | P-value* | |
|---|---|---|---|---|
| All IOIs combined, all joints | 7.21 | 1.65 | 1.62 (2007) | <0.01 |
| Individual IOIs, all joints | ||||
| Arthrodesis | 0.71 | 0.15 | 0.06 (2008) | <0.01 |
| Arthroplasty | 1.96 | 0.55 | 0.52 (2007) | <0.01 |
| Synovectomy | ||||
| Arthroscopic | 1.79 | 0.44 | 0.38 (2006) | <0.01 |
| Open | 1.10 | 0.15 | 0.13 (2007) | <0.01 |
| Radioscopic | 1.01 | 0.18 | 0.15 (2006) | <0.01 |
| Other IOIs | 1.86 | 0.29 | 0.29 (2010) | <0.01 |
| Individual joints, all IOIs | ||||
| Hip | 0.50 | 0.14 | 0.07 (2009) | <0.01 |
| Knee | 4.53 | 0.76 | 0.76 (2010) | <0.01 |
| Ankle | 2.24 | 0.52 | 0.38 (2009) | <0.01 |
| Shoulder | 0.17 | 0.06 | 0.03 (2007) | <0.01 |
| Elbow | 1.36 | 0.38 | 0.35 (2009) | <0.01 |
| Diagnosis | ||||
| Hemophilia A | 7.57 | 1.75 | 1.65 (2007) | <0.01 |
| Hemophilia B | 5.81 | 1.25 | 1.25 (2010) | <0.01 |
| Hemophilia severity | ||||
| Mild | 3.19 | 0.76 | 0.54 (2009) | <0.01 |
| Moderate | 5.34 | 1.41 | 1.36 (2009) | <0.01 |
| Severe | 9.27 | 2.10 | 2.03 (2007) | <0.01 |
| Age in years | ||||
| <20 | 3.86 | 0.71 | 0.56 (2009) | <0.01 |
| 20–39 | 11.23 | 2.56 | 2.32 (2008) | <0.01 |
| 40–59 | 14.04 | 3.06 | 2.81 (2007) | <0.01 |
| ≥60 | 8.51 | 2.48 | 1.63 (2009) | <0.01 |
| Inhibitor status | ||||
| Positive | 8.06 | 1.00 | 1.00 (2010) | <0.01 |
| Negative | 7.16 | 1.68 | 1.64 (2007) | <0.01 |
| Prophylaxis status | ||||
| Continuous prophylaxis | 4.61 | 1.57 | 0.12 (2007) | <0.01 |
| Intermittent or on demand | 12.06 | 2.29 | 2.24 (2008) | <0.01 |
*
Cochran–Armitage Trend Test.
IOI, invasive orthopedic intervention, represents a non-specific group of invasive orthopedic interventions not categorized as arthrodesis, arthroplasty or synovectomy.