Table 3. Change in Selected Edmonton Symptom Assessment Scale Symptoms in Dexamethasone and Placebo Arms.
| Variable | Dexamethasone | Placebo | P-value | ||||
|---|---|---|---|---|---|---|---|
| N | Mean (SD) | Change from Baseline (SD) | N | Mean (SD) | Change from Baseline (SD) | ||
| ESAS Fatigue | |||||||
| Baseline | 19 | 5.1 (2.3) | - | 19 | 3.4 (2.8) | - | - |
| Day 4 | 15 | 4.7 (2.4) | -0.7 (3.1) | 15 | 3.3 (2.1) | 0.4 (3.4) | 0.3 |
| Day 7 | 16 | 4.3 (2.2) | -1.2 (2.3) | 14 | 3.4 (2.2) | 0.5 (3.3) | 0.08 |
| Day 14 | 13 | 4.6 (1.7) | -0.8 (1.9) | 15 | 3.3 (1.9) | 0.5 (2.8) | 0.18 |
| ESAS Drowsiness | |||||||
| Baseline | 19 | 3.7 (2.7) | - | 19 | 1.8 (2.2) | - | - |
| Day 4 | 15 | 2.1 (2.2) | -2.2 (2.9) | 15 | 2.3 (2.6) | 0.7 (2.9) | 0.03 |
| Day 7 | 16 | 2.3 (2.3) | -1.8 (3.1) | 14 | 2.4 (1.9) | 1.1 (2.1) | 0.01 |
| ESAS Appetite | |||||||
| Baseline | 19 | 3.1 (2.6) | - | 19 | 3.3 (2.8) | - | - |
| Day 4 | 15 | 2.9 (3.6) | -0.4 (4.4) | 15 | 2.2 (2.2) | -1.1 (3.2) | 0.87 |
| Day 7 | 16 | 3.1 (3.3) | -0.2 (4.5) | 14 | 1.8 (1.9) | -1.4 (2.8) | 0.58 |
| Day 14 | 13 | 1.9 (2.2) | -1.5 (3.5) | 15 | 2.1 (2.7) | -0.9 (3.7) | 0.53 |
CI = confidence interval; ESAS = Edmonton Symptom Assessment System; SD =standard deviation.