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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Heart Rhythm. 2016 May 3;13(8):1699–1706. doi: 10.1016/j.hrthm.2016.05.002

Figure 1. PPARg cardiomyocytes have increased ROS and triggered activity.

Figure 1

A. ROS in isolated cardiomyocytes; height is DCF fluorescence minus background. ROS is reduced by mitotempo in PPARg cardiomyocytes. MT = mitotempo 20 μM. The means are significantly different by ANOVA, *= sig different from control by post-hoc test. Readings were performed in triplicate with 2000 cells/well from 3 animals of each type.

B. Graph of triggered activity from PPARg and control cardiomyocytes. The means are significantly different by ANOVA, *= sig different from control by post-hoc test, n=21–35 cells from 3 animals of each type.

C. Representative example of isolated control cardiomyocyte, paced without subsequent activity

D. Representative example of isolated PPARg cardiomyocyte with triggered activity after pacing.