Table 3.
Cox Proportional Hazards Models (All-cause mortality)
| Univariable | Multivariable | ||||
|---|---|---|---|---|---|
| Risk factors (variables in each factor being compared (detailed counts in Table 1)) |
Number of patients with data |
HR (95% CI) |
p-value | HR (95% CI) |
p-value |
| Stage 5 vs. 1/2/3A 4 vs. 1/2/3A 3b vs. 1/2/3A |
1052 |
3.8 (2.6–5.5) 1.9 (1.5–2.4) 1.4 (1.1–1.7) |
<.001 <.001 .007 |
3.0 (1.9–4.7) 1.5 (1.1–2.0) 1.1 (0.8–1.4) |
<.001 .004 .63 |
| Diabetes Mellitus (Y vs. N) |
1046 | 1.3 (1.1–1.6) | .006 | 1.4 (1.1–1.7) | .002 |
| Hypertension (Y vs. N) |
1043 | 0.9 (0.5–1.5) | .58 | ||
| Hyperlipidemia (Y vs. N) |
1041 | 0.9 (0.7–1.1) | .38 | ||
| Carotid Artery Disease (Y vs. N) |
1041 | 1.3 (1.1–1.6) | .001 | 1.5 (1.2–1.8) | <.001 |
| Stroke (Y vs. N) |
1041 | 1.2 (1.0–1.5) | .08 | ||
| Coronary Arterial Disease [CAD (Y vs. N)] |
1033 | 1.4 (1.2–1.7) | <.001 | ||
| Peripheral Arterial Disease (Y vs. N) |
1032 | 1.5 (1.2–1.8) | <.001 | ||
| Proteinuria (Y vs. N) |
842 | 2.2 (1.8–2.7) | <.001 | 1.8 (1.4–2.2) | <.001 |
| Family History of CAD (Y vs. N) |
966 | 1.1 (0.9–1.3) | .46 | ||
| Bilateral RAS (vs. Unilateral) |
952 | 1.3 (1.0–1.5) | .02 | ||
| Current Smoker (Y vs. N) |
894 | 1.3 (1.1–1.6) | .02 | ||
| Statin (Y vs. N) |
951 | 0.7 (0.57–0.87) | <.001 | 0.55 (0.42–0.70) | <0.001 |
| ACEi/ARB (Y vs. N) |
951 | 0.75 (0.59–0.96) | 0.02 | 0. 82 (0.63–1.06) | 0.12 |
| Calcium Channel Blocker (Y vs. N) |
951 | 0.77 (0.61–0.98) | 0.03 | 0.88 (0.68–1.13) | 0.31 |
| Beta Blocker (Y vs. N) |
951 | 1.0 (0.78–1.29) | 0.98 | ||
| Aspirin (Y vs. N) |
951 | 0.87 (0.67–1.12) | 0.28 | ||
| Plavix (Y vs. N) |
951 | 0.97 (0.82–1.22) | 0.97 | ||
| Warfarin (Y vs. N) |
951 | 0.97 (0.80–1.18) | 0.78 | ||
| Insulin (Y vs. N) |
951 | 1.3 (1.06 – 1.61) | 0.01 | ||
Definitions: HR-hazard ratio, CI- confidence interval