Table 5.
Comparison of methyl metabolites in plasma of control and TCE-treated mice. Results represent the mean (SD).
Plasma transmethylation metabolites | 0 mg/ml TCE | 0.01 mg/ml TCE | 0.1 mg/ml TCE |
---|---|---|---|
methionine (μM) | 52.90 (8.13) | 48.92 (6.88) | 44.42 (3.27) |
SAM (nM) | 268.40 (22.66) | 257.00 (39.70) | 191.33 (55.74)* |
SAH (nM) | 52.40 (15.35) | 49.25 (7.49) | 58.58 (16.03) |
SAM/SAH ratio | 5.44 (1.41) | 5.32 (1.13) | 3.40 (0.99)* |
Statistically different from the results obtained from controls (p≤0.05).