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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Addict Biol. 2016 Jan 24;22(3):616–628. doi: 10.1111/adb.12353

Figure 6. Adolescent ethanol exposure has no effect on the tonic GABAAR current of pyramidal neurons in layer II/III of the adult PrL-C.

Figure 6

A) Representative traces showing the effect of picrotoxin (100 μM) on GABAAR tonic currents in layer II/III pyramidal neurons. B) AIE had no effect on picrotoxin-sensitive GABAAR tonic current in pyramidal neurons of layer II/III (n = 4-6 cells/group). C) Representative traces showing current mediated by δ-subunit containing GABAAR receptors in layer II/III pyramidal neurons measured using the δ-GABAAR agonist THIP (1 μM). D) THIP-mediated changes in the holding current revealed that AIE had no effect on δ-GABAAR current amplitude in layer II/III of PrL-C (n= 5-6 cells/group).