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Ganoderma lucidum ribonuclease promoted UPR in colorectal cancer cells. After treatment with GLR at the indicated concentrations for 24 or 48 h, the protein levels of IRE1α, ATF6, PERK, caspase-12, and CHOP in HT29 cells (A) and HCT116 cells (B) were determined by western blotting. GAPDH was used as an internal control.
