Table 2.
Studies about fasting plasma glucose as a screening test
| n | Cut-off mmol/L | Se (%) | Sp (%) | GDM (%) | AUC | Glucose load (g) | OG criteria1 | Ref. |
| Without selection bias | ||||||||
| 5010 | 4.5 | 81.5 | 54 | 7.6 | -- | 75 | WHO-1985 | Reichelt et al[37] |
| 558 | 4.8 | 81 | 76 | 10.2 | 0.897 | 100 | ADA | Perucchini et al[27] |
| 942 | 4.1 | > 70 | 13 | 0.766 | 75 | WHO-1985 | Tam et al[38] | |
| 1685 | 4.7 | 78.1 | 32.2 | 19.8 | 0.639 | 75 | WHO-1999 | Agarwal et al[39] |
| 500 | 4.7 | 88 | 95 | 7.2 | -- | 100 | C and C-1982 | Poomalar et al[41] |
| In early pregnancy | ||||||||
| 4507 | 4.6 | 80 | 43 | 6.7 | 0.7 | 75 | Sacks | Sacks et al[46] |
| 708 | 4.7 | 79.9 | 27.5 | 25.9 | 0.579 | 75 | WHO-1999 | Agarwal et al[47] |
| 4876 | 4.4 | 79 | 46.9 | 2.8 | 0.72 | 100 | C and C 100-g OGTT | Riskin-Mashiah et al[49] |
| 17186 | 4.3 | 84 | 29 | 12.4 | -- | 75 | IADPSG | Zhu et al[51] |
| 486 | -- | 47.2 | 77.4 | 10.9 | 0.623 | -- | FPG > 5.1 mmol/L | Yeral et al[53] |
1
Fasting plasma glucose (FPG) threshold with Specificity (Sp) corresponding to Sensitivity (Se) about 80%. AUC: Area under receiver operating characteristic curve; C and C: Carpenter-Coustan; ADA: American Diabetes Association; WHO: World Health Organization; IADPSG: International Association of Diabetes and Pregnancy Study Groups; OGTT: Oral glucose tolerance test; GDM: Gestational diabetes mellitus.