Table 5.
Diagnostic role of transcranial Doppler and its accuracy
| Ref. | No. of patients | Sensitivity (%) | Specificity (%) | Accuracy (%) | Cut-off for RLS |
| Serena et al[48], 1998 | 55 | 100 | 100 | 100 | ≥ 1 MES1 |
| Lange et al[49], 2010 | 26 | 31 | 100 | 65.5 | ≥ 9 MES |
| González-Alujas et al[52], 2011 | 93 | 97 | 98 | 97.5 | ≥ 1 MES |
| Mojadidi et al[51], 2014 | 1968 | 97 | 93 | 95 | Meta-analysis2 |
1
In this study c-TCD performs better than c-TEE;
2
This study is a large meta-analysis comprising 27 studies. TCD: Transcranial Doppler; c-TCD: Contrast enhanced TCD; TEE: Transesophageal echocardiography; RLS: Right-to-left shunting; MES: Microembolic signals.