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. 2016 Jul 26;8(7):413–424. doi: 10.4330/wjc.v8.i7.413

Table 1.

Epidemiological and clinical features of takotsubo cardiomyopathy

Tsuchihashi et al[15] Núñez et al[14] Kurowski et al[13] Eshtehardi et al[16] Parodi et al[11] Ahmed et al[17] Templin et al[18]
Country Japan Spain Germany Swiss Italy United States Europe and United States
Year of publication 2001 2015 2007 2009 2007 2013 2015
Subjects, n 88 202 35 41 36 620 (systematic review) 1750 (international registry)
Age (yr) 67 ± 13 70 ± 12.5 72 ± 9 65 ± 11 75 ± 7 67 66.8 ± 13
In percentage (%)
Reported incidence1 --- 1.2 1.2 1.7 2 --- ---
Women 86 90 94 85 1006 91 89.8
Hypertension 48 67 74 56 50 --- 65
Diabetes 12 15 23 5 5.5 --- 14
Hyperlipidemia 24 41 34 39 39 --- 31
Current smoking --- 15 20 27 19 --- 20
Apical type 1003 --- 60 --- --- --- 81.7
Emotional/psychological trigger 20 50 43 46 --- 41 27.7
Physical (acute diseases, exercise, surgery and medical procedures) trigger 53 20 43 17 --- 45 36
No identified triggering factor 26 27 14 37 28 14 28.5
Chest pain 67 80 --- 76 1002 54 76
Dyspnea 7 45 --- 24 --- 26 47
Syncope --- 9 --- --- --- --- 7.7
ST segment elevation 90 62 69 39 1002 39 43.7
T wave inversion 97 94.4 --- 46 --- 31 415
In hospital mortality 1 2.44 9 0 --- 4 4.1
Long term mortality from all causes --- --- 8.6 (at 12 mo) 2 (23 ± 10 mo) 3 (at 6 mo) --- 5.6 (per patient-year)
Recurrences 2.7 0 6 5 --- --- 1.8 (per patient-year)
1

Incidence is based on patients with acute coronary syndrome;

2

This case series included only patients with chest pain and ST segment elevation;

3

Included only the typical form (apical ballooning);

4

All from noncardiac causes;

5

On admission;

6

Only included women.