Table 3.
Ref. | Year | No. of patients | Study design | Criteria | AFP cut-off values |
Yang et al[56] | 2007 | 63 | Retrospective | AFP | 20 ng/mL, 200 ng/mL, 1000 ng/mL |
Tumor size | |||||
Number of tumors | |||||
Zheng et al[63] | 2008 | 195 | Retrospective | AFP | 400 ng/mL |
Total tumor diameter | |||||
Histopathologic grade | |||||
Lai et al[64] | 2012 | 158 | Retrospective | AFP | 400 ng/mL |
Total tumor diameter | |||||
Duvoux et al[57] | 2012 | 435 | Prospective | AFP | 100 ng/mL, 1000 ng/mL |
Tumor size | |||||
Number of tumors | |||||
Kashkoush et al[76] | 2014 | 115 | Retrospective | AFP | 400 ng/mL |
Actual tumor volume | |||||
Toso et al[75] | 2015 | 233 | Prospective | AFP | 400 ng/mL |
Total tumor volume | |||||
Hong et al[77] | 2015 | 123 | Retrospective | AFP | 200 ng/mL |
F-FDG PET positivity |
AFP: Alpha-fetoprotein; F-FDG PET: F-fluorodeoxyglucose positron emission tomography.