Table 1. Vital signs 2 hours after instillation of saline, 3 or 6 mg/kg LPS.
Vital signs | Variable ± SD | ||
---|---|---|---|
Saline (n=10) | LPS (3 mg/kg) (n=10) | LPS (6 mg/kg) (n=10) | |
Heart rate, bpm | 420±17 | 390±72 | 382±63 |
Systemic blood pressure, mmHg | 118±15 | 68±10a | 61±8a |
PaO2/FiO2 index | 524±56 | 280±16a | 212±12a |
Mean B-lineper animal | 2.40±1.35 | 11.10±4.53a | 20.10±6.62a |
a, P<0.0001 vs. saline. LPS, lipopolysaccharide; SD, standard deviation.