Figure 3.
Forest plot for NOX activity or mRNA expression. A random effect model was used due to significant heterogeneity of publications (I2=87.9, P<0.01). Effect size was assessed by Hedges’s g and 95% CI, and the effect of NOX mRNA expression or NOX activity was slightly in favor of lung cancer, but it was not statistically significant (Hedges’s g =0.610, P=0.384). NOX, NADPH oxidase; CI, confidence interval.