Table 3. Univariate and multivariate Cox regression analysis of OS of thymic carcinoma patients.

Variables	Univariate				Multivariate
	HR	95% CI	P value		HR	95% CI	P value
Age
≤60
>60	1.362	0.526–3.527	0.524
Sex
Male
Female	2.203	0.869–5.585	0.096
Tumor size	1.029	0.895–1.184	0.687
Histologic classification (squamous cell)
Basaloid	3.563	0.452–28.071	0.228
Lymphoepitheliema-like	2.775	0.356–21.643	0.330
Neuroendocrine	0.754	0.171–3.324	0.709
Differentiation
High
Moderately	0.179	0.011–2.928	0.227
Low	1.100	0.142–8.506	0.927
Masaoka stage
IIA and IIB
IIIA and IIIB	3.183	0.639–15.861	0.158		3.807	0.733–19.782	0.112
IVA and IVB	11.111	2.416–51.107	0.002		7.773	1.559–38.768	0.012
Neutrophil count	1.074	0.924–1.248	0.351
Lymphocyte count	0.551	0.248–1.223	0.143
Platelet count	0.993	0.984–1.002	0.125
NLR	1.342	1.091–1.650	0.005		0.833	0.505–1.373	0.473
1st quartile
2nd quartile	6.656	0.799–55.472	0.080		5.148	0.581–45.591	0.141
3rd quartile	2.134	0.193–23.605	0.536		1.966	0.150–25.834	0.607
4th quartile	12.836	1.615–101.990	0.016		14.641	0.679–315.919	0.087
PLR	1.005	1.000–1.010	0.052
1st quartile
2nd quartile	0.943	0.210–4.236	0.939
3rd quartile	3.342	0.828–13.491	0.090
4th quartile	1.894	0.452–7.940	0.382
Surgical approach
Open surgery
VATS	0.934	0.124–7.050	0.948
Adjuvant therapy
Radiotherapy	4.204	0.558–31.696	0.164
Chemotherapy	0.999	0.396–2.518	0.997

HR, hazard ratio; CI, confidence interval; OS, overall survival; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; VATS, video-assisted thoracoscopic surgery.