Figure 3.

Voxel-wise mean glucose metabolism and PiB binding across young, PiB− OLD, PiB+ OLD, and Alzheimer’s disease subjects. Voxel-wise mean FDG and PiB values are overlaid on semi-inflated lateral and medial surfaces of the brain for young (A), PiB− OLD (B and F), PiB+ OLD (C and G), and Alzheimer’s disease (D and H) groups. The top row (A–D) displays the FDG data while the bottom row (F–H) displays the PiB data with an exception that, for young subjects (E), a map of region of interest-based high (grey) and low (orange) metabolism regions is shown instead of the PiB data. Scale represents raw FDG SUVR and PiB DVR values, respectively.