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Schematic representations of the extracellular regions of the three chimeric TSHR–LH/CGR mutants. The Mc1 + 2, Mc2, and Mc4 chimera receptors. Green, human TSHR sequence (WT); red, homologous regions of the rat LH/CGR that were used to substitute for the deleted TSHR sequences. The numbers assigned to the amino acids are determined by counting from the methionine start site.
