Skip to main content
. 2016 Jul 25;6:30207. doi: 10.1038/srep30207

Figure 2. Enhanced directional movement of breast cancer-affected mDCs toward CCL19.

Figure 2

(a,b) Box-and-whisker plots of the velocity (a) and directional persistence (b) of mature DCs (mDC only) or mDCs co-incubated with MCF-10A (mDC-MCF-10A), MCF-7 (mDC-MCF-7), MDA-MB-231 (mDC-MDA-MB-231), MDA-MB-436 (mDC-MDA-MB-436) or SK-BR-3 (mDC-SK-BR-3) in response to CCL19. (c,d) Histograms of the velocity (c) and directional persistence (d) of mDC only, mDC-MCF-10A, mDC-MCF-7, mDC-MDA-MB-231, mDC-MDA-MB-436 or mDC-SK-BR-3. The mean velocity and directional persistence of mDC only are indicated by a dotted line. n ≥ 70. (e) Flow cytometric analysis of CCR7 expression on the indicated groups. (f) Data represent mean ± s.e.m. of at least three independent experiments described in (e). Data was normalized by mDC only (value = 1). *P < 0.05 and ***P < 0.001.