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. 2016 Jul 25;6:30301. doi: 10.1038/srep30301

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Copyright © 2016, The Author(s)

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Results showed that HS rats had higher protein expression of NOX2 and NOX4 compared with NS rats (P < 0.05, n = 7). 15-week of CoQ10 administration by gavage at the dose of 10 mg/kg/day significantly decreased NOX2 and NOX4 expression (P < 0.05, n = 7). (A) Representative immunoblot of NOX2 and NOX4. (B) Densitometric analysis of protein expression of NOX2. Effects of CoQ10 on NAD (P) H oxidase subunit NOX2 and NOX4 in the PVN in different groups. Values are expressed as means ± SE. *P < 0.05 vs control (NS + oil or NS + CoQ10), ^†P < 0.05, HS + CoQ10 vs HS + oil.