Skip to main content
. 2016 Jul 25;6:30272. doi: 10.1038/srep30272

Figure 6. Activation of AMPK with AICAR reduced Sesn2 siRNA induced neurological deficits, cerebral infarct volume and oxidative stress.

Figure 6

(A) Neurological scores in the Sesn2 siRNA group and Sesn2 siRNA + AICAR group at 24 hours following cerebral I/R. (B) Cerebral infarct volume in the Sesn2 siRNA group and Sesn2 siRNA + AICAR group at 24 hours following cerebral I/R. (C) SOD activity in the Sesn2 siRNA group and Sesn2 siRNA + AICAR group. (D) Histograms showing the MDA levels in the Sesn2 siRNA group and Sesn2 siRNA + AICAR group. Error bars represent mean ± SEM. (*p < 0.05; **p < 0.01; ***p < 0.001). Panel A: n = 10 per group; Panel (C–E): n = 5 per group.