TABLE 5.

Factors Associated with Cardiac Death or Retransplantation

Variables	Univariate Analysis			Multivariate Analysis
	HR	95% CI	p	HR	95% CI	p
Recipient age, per 1 year	0.97	0.945–0.999	0.04	0.98	0.94–1.01	0.16
Diabetes at baseline	1.40	0.22–5.27	0.67
Hypertension at baseline	0.30	0.02–1.52	0.17
Hyperlipidemia at baseline	0.20	0.01–1.02	0.05	0.16	0.01–1.00	0.05
Total cholesterol at 1 year, per 1 mg/dl	1.01	0.99–1.02	0.27
Triglycerides at 1 year, per 1 mg/dl	1.00	0.99–1.00	0.997
LVEF at 1 year, per −1%	1.01	0.94–1.07	0.79
Acute cellular rejection ≥grade 2R during the first year	2.92	0.93–8.86	0.06
rATG	1.72	0.08–14.78	0.66
Tacrolimus	0.58	0.09–2.29	0.47
Sirolimus	2.63	0.84–7.99	0.09
Female donor	1.87	0.57–5.61	0.29
Donor-recipient sex mismatch	0.63	0.10–2.34	0.53
Baseline intimal volume, per 1 mm3/mm	1.00	0.67–1.36	0.99
Baseline percent intimal volume, per 1%	1.01	0.94–1.08	0.68
Donor atherosclerosis (MIT at baseline ≥0.5 mm)	1.03	0.34–3.41	0.96
ASP at baseline	0.43	0.02–2.19	0.36
Increase in MIT ≥0.5 mm during the first year	1.12	0.17–4.22	0.88
Increase in intimal volume, per 1 mm3/mm	1.10	0.54–2.07	0.79
Increase in percent intimal volume, per 1%	1.07	0.98–1.18	0.14
Decrease in vessel volume, per 1 mm3/mm	1.33	0.94–1.89	0.11
Decrease in lumen volume, per 1 mm3/mm	1.33	0.95–1.89	0.10
ASP progression	4.83	1.45–14.66	0.01	6.58	1.70–26.33	0.008
Calcium progression	0.79	0.12–2.94	0.75
Paradoxical vessel remodeling of the proximal LAD segment	13.84	2.72–252.29	0.0004	10.35	1.98–190.65	0.003

All variables with a p value of ≤ 0.05 on univariate analysis were included in multivariate analysis.

Abbreviations as in Tables 1, 2, and 4.