Table 2.
Incidence of death, delisting and HTx while listed and comparison of the likelihood of HTx among the 3 clinical cohorts.
| Events while listed | Likelihood of HTx | ||||||
|---|---|---|---|---|---|---|---|
| Death | Death/Delisting | HTx | HR (95% CI) ‡ | p-value | HR (95% CI) § | p-value | |
| Clinical Course | |||||||
| MED group (n=11009) | 1.15/100PM | 1.83/100PM | 7.94/100PM | 1.000 | |||
| Delayed-LVAD group (n=1590) | 0.30/100PM | 0.62/100PM | 5.70/100PM | 0.968 (0.921-1.017) | 0.190 | 1.000 | |
| Early-LVAD group (n=1588) | 0.65/100PM | 1.19/100PM | 11.77/100PM | 1.389 (1.307-1.477) | <0.001 | 1.435 (1.339-1.538) | <0.001 |
| Waitlist Status when being listed | |||||||
| Listed as UNOS status 1A | |||||||
| MED group (n=1711) | 5.23/100PM | 8.95/100PM | 31.30/100PM | 1.000 | |||
| Delayed-LVAD group (n=325) | 0.63/100PM | 1.04/100PM | 7.36/100PM | 0.627 (0.563-0.699) | <0.001 | 1.000 | |
| Early-LVAD group (n=777) | 1.15/100PM | 2.07/100PM | 17.00/100PM | 0.980 (0.889-1.081) | 0.690 | 1.563 (1.395-1.751) | <0.001 |
| Listed as UNOS status 1B | |||||||
| MED group (n=3853) | 1.98/100PM | 3.10/100PM | 17.00/100PM | 1.000 | |||
| Delayed-LVAD group (n=718) | 0.30/100PM | 0.73/100PM | 6.22/100PM | 0.651 (0.603-0.702) | <0.001 | 1.000 | |
| Early-LVAD group (n=737) | 0.34/100PM | 0.66/100PM | 8.90/100PM | 0.756 (0.696-0.820) | <0.001 | 1.161 (1.056-1.277) | 0.002 |
‡
Comparison analysis being adjusted by age, gender, race, blood type, and coexisting of diabetes mellitus, MED group as a reference
§
Comparison analysis being adjusted by age, gender, race, blood type, and coexisting of diabetes mellitus, Delayed-LVAD group as a reference
HTx indicates heart transplantation; MED, medically treated; LVAD, left ventricular assist device; 100MP, 100 person-month; HR hazard ratio; CI, confidential interval.