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. 2016 Aug;358(2):324–333. doi: 10.1124/jpet.116.231928

TABLE 2.

Recovered estimates of d8-TCA total uptake clearance (CLUptake), basolateral efflux clearance (CLBL), biliary clearance (CLBile), and KFlux in the presence of 4% BSA

Estimates were based on the model scheme and time-course data depicted in Fig.1. The model was fit to data generated from n = 3 independent SCHH preparations (triplicate measurements) separately.

Parameter Estimate Mean SD CV%
CLUptake (mL/min/g liver) 0.63 0.12 20
CLBL (mL/min/g liver) 0.034 0.011 32
CLBile (mL/min/g liver) 0.074 0.030 36
KFlux (min−1) 0.018 0.0015 8