Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mean metabolic ratios of (A) R-BUP/S-BUP, (B) RR-OHBUP/SS-OHBUP, (C) SR-ERYHBUP/RS-ERYHBUP, and (D) RR-THRHBUP/SS-THRHBUP over time in 15 healthy volunteers after a single 100-mg oral dose of racemic BUP. The inset in (D) illustrates the switch in ratio directionality after 6 hours. Symbols and error bars denote observed mean ratios and lower limits of the 95% confidence interval, respectively.
