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CB1 receptors play a necessary role in the SA-57 discriminative stimulus. (A) Rimonabant (0.3–3 mg/kg) significantly attenuated the SA-57 training dose. (B) Rimonabant doses (i.e., 0.1, 0.3, 1, 3 mg/kg) that blocked the SA-57 training dose did not reduce response rates. Values represent mean ± S.E.M.; n = 3–6 mice/group.
