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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Curr Med Res Opin. 2016 Mar 2;32(6):991–996. doi: 10.1185/03007995.2016.1149056

Table 2.

Clinical trials used for individual patient data reconstruction organized by treatment line.

Study (year) Treatment(s) Treatment
line
Reference
Swain et al. (2013) Pertuzumab + trastuzumab +
docetaxel
First 9
Swain et al. (2013) Trastuzumab + docetaxel First 9
Verma et al. (2012) T-DM1 Second 10
Blackwell et al. (2010) Trastuzumab + lapatinib Second 13
Geyer et al. (2006) Capecitabine + lapatinib Third 12
von Minckwitz et al.
  (2009)
Trastuzumab + capecitabine Third 11
Blackwell et al. (2010) Trastuzumab + lapatinib Third 13

T-DM1: trastuzumab emtansine.