TABLE 4.
E. coli O104:H4-specific proteins targeted for secretion and accumulating in minimal medium
| O104:H4 recorda | NCBI and KEGG annotation | NSAF |
|---|---|---|
| gi|407484719 | β-Lactamase class A CTX-M | 2.26E−02 |
| gi|407479883 | Hypothetical protein O3K_01500 | 1.50E−02 |
| gi|407484873 | Esp; serine protease autotransporter | 9.01E−03 |
| gi|407482751* | StxB; Shiga toxin 2 subunit B | 7.09E−03 |
| gi|407484724 | β-Lactamase class A TEM | 5.24E−03 |
| gi|407481333 | Hypothetical protein O3K_08885 | 4.38E−03 |
| gi|407479888 | CusF; Cu(I)/Ag(I) efflux system periplasmic protein | 2.47E−03 |
| gi|407479899 | PcoC; copper-resistant protein | 2.28E−03 |
| gi|407481442 | Hypothetical protein O3K_09440 | 1.60E−03 |
| gi|407483433* | Hypothetical protein O3K_19565 | 1.50E−03 |
| gi|407480423 | Hypothetical protein O3K_04210 | 1.42E−03 |
| gi|407484167* | 3-Demethylubiquinone-9 3-methyltransferase | 9.82E−04 |
| gi|407482619 | Hypothetical protein O3K_15445 | 8.48E−04 |
| gi|407484687 | EDTA-resistant nuclease | 8.39E−04 |
| gi|407479891 | Hypothetical protein O3K_01540 | 8.36E−04 |
| gi|407482628 | TerD; tellurium resistance protein | 7.42E−04 |
| gi|407481443; gi|407482620 | Hypothetical protein O3K_09445 | 6.26E−04 |
| gi|407480299 | Putrescine 2-oxoglutarate aminotransferase | 6.25E−04 |
| gi|407481503* | HchA; molecular chaperone | 6.04E−04 |
| gi|407484827 | Fimbrial subunit AAF/1 | 6.03E−04 |
| gi|407484114 | Ferric aerobactin receptor | 5.57E−04 |
| gi|407480477; gi|407484128 | Esp; serine protease autotransporter | 5.12E−04 |
| gi|407482275 | Hydrolase | 4.88E−04 |
| gi|407480362* | Oxidoreductase, short-chain dehydrogenase/reductase family protein | 4.11E−04 |
| gi|407482134 | FimC; fimbrial chaperone protein | 3.90E−04 |
| gi|407483057 | NmpC; outer membrane porin protein LC | 3.68E−04 |
| gi|407481484 | FyuA; pesticin/yersiniabactin receptor | 2.74E−04 |
| gi|407479602* | Hypothetical protein O3K_00075 | 2.63E−04 |
| gi|407482682* | Outer membrane receptor for ferrienterochelin and colicins | 1.39E−04 |
| gi|407484105 | Esp; serine protease autotransporter | 1.01E−04 |
| gi|407480464 | Hypothetical protein O3K_04430 | 9.77E−05 |
a
Asterisks indicate proteins with identity of ≥90% to O157:H7 counterparts but not detected in O157:H7 medium. Records without asterisks are proteins considered unique to O104:H4 (identity of <90% with O157:H7 counterparts).