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. Author manuscript; available in PMC: 2017 Mar 7.
Published in final edited form as: Curr Biol. 2016 Feb 18;26(5):616–626. doi: 10.1016/j.cub.2015.12.069

Figure 5. Connectivity Modulates the Contractile Response of Actin Rings.

Figure 5

(A) Schematic illustration (left) of the connectivity C of different actin filament generated by the Arp2/3 complex (red symbols) and α-actinin (black symbols). The network connectivity is the average of all filament connectivity values. It is expected to increase as a function of the number of connecting crosslinkers present in the system (right).

(B) Maximal velocity of perimeter deformation for the different actin rings as a function of the network connectivity.

(C) Size of the largest percolating cluster (normalized to the total number of actin filaments) as a function of the network connectivity, for branched network (green), ordered bundles (red), and disordered bundles (blue). Vertical lines indicate the threshold at which percolation is considered reached (i.e., 95% of filaments are connected).

(D) Variation of the maximal velocity for a define ring architecture (disordered networks green, ordered bundles red) with different initial configuration (variable number of primers for disordered networks green or ordered bundles red, see Experimental Procedures) as a function of the network connectivity.