Fig. 46 (abstract P117).

a Cytotoxicity of WYE354 (WYE) and Sunitinib (SUT) in K562 and the combination of these inhibitors at 48hrs. b Combination index plot showing CI values at different doses of WYE and SUT when combined. c Annexin V staining showing total % apoptotic cells using three different doses of WYE and SUT. Results represent mean of three independent experiments and unpaired t test is performed to determine the statistical significance between treated groups vs control