FIGURE 5.
PET images of 89Zr-DFO-mAb-B43.13 demonstrating the progression of LN metastasis. (A) Coronal (top) and maximum-intensity projection (MIP; bottom) PET image obtained 72 h after the administration of 89Zr-DFO-mAb-B43.13 to a mouse 8 wk after implantation of an OVCAR3 xenograft on the right shoulder. (B) Coronal (top) and MIP (bottom) PET images obtained 72 h after the administration of 89Zr-DFO-mAb-B43.13 to the same mouse 11 wk after the implantation of the OVCAR3 xenograft on the right shoulder. (C) PET/CT image obtained 120 h after the administration of 89Zr-DFO-mAb-B43.13 to the same mouse 11 wk after the implantation of the OVCAR3 xenograft on the right shoulder. ALN = axillary LNs; BLN = brachial LN; L = liver; max = maximum; min = minimum; p.i. = after injection; SMLN = submandibular LN; T = tumor.