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. Author manuscript; available in PMC: 2016 Jul 25.
Published in final edited form as: J Med Chem. 2015 Nov 16;58(22):8896–8906. doi: 10.1021/acs.jmedchem.5b01187

Figure 2.

Figure 2

Dose-response curve for compounds 7f, 8 and PTL against rat gliosarcoma cells (9L-SF): Cell survival as a function of drug concentration for cells treated for 48 h with the indicated drug. Each datum point represents the mean plus standard error of the mean for three experiments. Drugs 7f and 8 were markedly more toxic than DMAPT, with drug 8 being one million-fold more toxic than DMAPT at a concentration of 10 μM.