TABLE 3.
Results of BLAST comparison of proteins encoded by lctLMG operon with Entrez protein database
| ORF | No. of amino acids (position)a | Protein with greatest homology (accession no.) | Predicted domain(s) or superfamily encoded by ORF | Organism | Amino acid identity (%) |
|---|---|---|---|---|---|
| lmgA | 49 (bp 118–267) | Lantibiotic nukacin (WP_037580734.1) | Type A lantibiotic (pfam04604) | Streptococcus equi | 69 |
| lmgA | 49 (bp 118–267) | Lantibiotic lacticin 481 (WP_032489363.1) | Type A lantibiotic (pfam04604) | Lactococcus lactis | 73 |
| lmgM | 884 (bp 757–3411) | Lacticin 481/lactococcin biosynthesis protein LcnDR2 (WP_032489360.1) | Lantibiotic-modifying enzyme (COG4403), cyclases involved in biosynthesis of class II lantibiotics (cd04792) | Lactococcus lactis | 45 |
| lmgT | 696 (bp 3420–5510) | Lacticin 481/lactococcin DR transport/processing ATP-binding protein LcnDR3 (WP_032489362.1) | Peptidase C39 family (pfam03412) | Lactococcus lactis | 53 |
| lmgF | 303 (bp 5587–6498) | Bacitracin transport ATP-binding protein BcrA (CIT27467.1) | ATP-binding cassette domain of bacitracin-resistance transporter (cd03268) | Streptococcus pneumoniae | 65 |
| lmgE | 250 (bp 6498–7250) | NukE (AKQ51582.1) | ABC-2 family transporter protein (pfam12730), lantibiotic protection ABC transporter permease subunit (TIGR03733) | Staphylococcus epidermidis | 48 |
| lmgG | 245 (bp 7247–7984) | NukG (AKQ51591.1) | Predicted lantibiotic-exporting membrane permease, EfiE/EfiG/ABC2 family (COG4200) | Staphylococcus epidermidis | 49 |
a
The number of amino acids and the position of the lctLMG operon from the beginning of the sequence are given for each ORF.