Fig. 3.

ET allows the network SR (nSR) to be distinguished and followed throughout the cell. (A) jSR (left panel, arrow) and nSR can be accurately followed by 3D image rotation (middle and right, arrows pointing out the continuity between jSR and nSR). Scale bar = 500 nm. (B) A schematic representation of difficulties in identifying nSR in 2D micrographs if the section is cut in a sub-optimal plane. (C) An example of nSR network visualised at a different virtual “cutting plane” – what appears to be unidentifiable vesicles (right, arrows) is in fact part of larger nSR web.