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. 2016 Apr 5;7(2):e00431-16. doi: 10.1128/mBio.00431-16

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Copyright © 2016 Bacharach et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Genomic characterization of the segments of TiLV isolated from tilapia in Israel. (A) TiLV segment 1 putative protein shows weak homology to motifs conserved in RNA-dependent polymerases. Sequence comparison of TiLV’s segment 1 predicted protein with motifs I to IV, conserved in polymerases of influenza virus strains C/JJ/50 (Inf C) (19), A/WSN/33 (Inf A) (34), and B/Lee/40 (Inf B) (35), vesicular stomatitis virus (VSV) (20), human immunodeficiency virus (HIV) (21), and poliovirus (Polio) (22). The relative motif positions are also shown. Invariant sequences in each motif are in boldface and underlined. TiLV sequences that show identity to one of the influenza virus sequences are highlighted in yellow. (B) Genomic segments of TiLV show conserved and homologous features at 5′ and 3′ termini.