Table 2.
Cortical volume measurements for select brain regions obtained using Freesurfer (N = 124)
| Brain Region (volume/mm3) |
HIV+ with trauma (n = 32) M(SD) |
HIV− with trauma (n = 31) M(SD) |
HIV+ without trauma (n = 30) M(SD) |
HIV− without trauma (n = 31) M(SD) |
p |
|---|---|---|---|---|---|
| Left frontal lobe | 725.84 (174.27) | 783.22 (163.14) | 713.60 (126.20) | 779.96 (141.11) | 0.400 |
| Right frontal lobe | 988.09 (239.23) | 974.19 (222.51) | 912.43(165.85) | 939.77 (158.70) | 0.384 |
| Left ACC | 1547.06 (410.37) | 1866.45 (554.08) | 1675.33 (470.46) | 1596.90 (410.84) | 0.076 |
| Right ACC | 1773.34 (421.83) | 2020.83 (444.02) | 2098.86 (557.52) | 2018.03 (480.70) | 0.044* |
| Left hippocampus | 3369.50 (461.37) | 3591.54 (375.08) | 3829.46 (435.37) | 3631.19 (362.81) | 0.000** |
| Right hippocampus | 3385.09 (426.98) | 3615.00 (333.11) | 3779.03 (525.48) | 3551.41 (462.85) | 0.004** |
| Corpus Callosum | 2731.84 (516.66) | 3215.48 (534.92) | 3052.36 (581.53) | 3097.41 (438.96) | 0.009** |
| Left Amygdala | 1266.43 (211.40) | 1355.41 (210.58) | 1390.33 (168.74) | 1315.16 (196.04) | 0.054 |
| Right Amygdala | 1400.90 (247.36) | 1451.58 (243.44) | 1431.10 (193.84) | 1410.61 (228.58) | 0.569 |
| Left caudate | 3228.37 (438.61) | 3564.51 (467.31) | 3715.60 (501.04) | 3513.22 (457.39) | 0.003** |
| Right caudate | 3459.56 (433.37) | 3766.74 (474.05) | 3885.10 (509.06) | 3659.38 (429.03) | 0.008** |
| Left putamen | 5156.31 (639.81) | 5872.45 (570.78) | 5550.63 (768.79) | 5633.74 (708.07) | 0.006** |
| Right putamen | 4999.71 (501.91) | 5621.90 (619.95) | 5426.06 (587.93) | 5379.03 (647.67) | 0.008** |
Note: HIV + = HIV positive; HIV − = HIV negative; ACC = Anterior Cingulate Cortex
*
p < 0.05;
**
p < 0.01