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. Author manuscript; available in PMC: 2016 Jul 25.
Published in final edited form as: Int J Clin Pharmacol Toxicol. 2016 May 19;5(3):209–215.

Figure 4.

Figure 4

Monte-Carlo simulation results illustrating Metoprolol pharmacokinetic profiles for 5000 virtual patients and dose-finding simulation results identifying equivalent systemic drug exposures measured as area under the concentration-time curve.