Table 3. Efficacy results.
| Patient ID | Doses of EndoTAG-1/Paclitaxel | % Decrease in MRI-tumor volume | % Decrease in MRI-max diameter | % decrease in tumour perfusion (Ktrans) | pCR | RCB | |
|---|---|---|---|---|---|---|---|
| Continuous | Class | ||||||
| 1 | 12 | -100.00 | -100.00 | -90.76 | Yes | 0 | 0 |
| 2 | 12 | -95.28 | -52.94 | -9.03 | No | 1.641 | 2 |
| 3 | 12 | -90.12 | -66.18 | NA | No | 1.395 | 2 |
| 4 | 12 | -83.85 | -33.03 | -43.92 | No | Not assessed | Not assessed |
| 5 | 1 | -94.34 | -45.92 | -14.43 | Yes | 0 | 0 |
| 6 | 6 | -87.34 | -22.43 | -42.42 | Yes | 0 | 0 |
| 7 | 6 | -0.46 | -0.29 | -35.89 | No | 3.993 | 3 |
| 8 | 12 | -99.38 | -82.66 | -11.53 | Yes | 0 | 0 |
| 9 | 2 | -85.26 | -35.53 | -68.52 | No | 1.828 | 2 |
| 10 | 12 | -68.62 | -56.57 | 0.41 | No | Not assessed | Not assessed |
| 11 | 1 | -50.43 | -43.78 | -30.97 | No | 3.718 | 3 |
| 12 | 12 | -98.51 | -51.09 | -91.55 | No | 3.92 | 3 |
| 13 | 12 | -100.00 | -63.60 | NA | Yes | 0 | 0 |
| 14 | 12 | -100.00 | 54.36 | -86.21 | No | 1.687 | 2 |
| 15 | 9 | -60.35 | -23.20 | -4.46 | No | 4.299 | 3 |
Abbreviations: ID: Identifier, MRI: Magnetic Resonance Imaging, NA: Not Assessed, pCR: pathologic Complete Response, RCB: Residual Cancer Burden