Figure 4.

At 3 months after grafting, in the absence of dexamethasone treatment, subretinal injection of hRPC into WT rats had no significant impact on either visual acuity. The rats tracked well at all spatial frequencies tested by OKR: 0.125 C/D (A), 0.25 C/D (B), and 0.125 C/D (C), with time spent tracking the visual stimulus not significantly affected by either hRPC transplantation (0 vs. 50 K) or eye (left versus right). (D) Representative retinal images from the left (L) and right (R) eyes of vehicle-injected (0 K) and hRPC-injected (50 K) animals. (E) There were no statistically significant differences in ONL thickness between either transplant group (0 vs. 50K) or between left and right eyes. Graphs show the mean ± SEM, DAPI-stained nuclei in blue. Scale bars: 50 μm.