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Insulin-dependent Akt phosphorylation in the liver from C57BL/6J mice. Histogram represents means of Akt phosphorylation in skeletal muscle from C57Bl6J mice (same groups of mice as in Fig. 1). The abundance of Akt phosphorylated at Ser 473 was normalized to total Akt abundance using specific antibodies. Data are means ± SEM (n = 7–8 experiments per group). Representative pictures of samples from each group are reported. * P < 0.05 versus control group (t-test).
