TABLE 2.
Mean transit times, residence times, FCRs, and recycling numbers in neonatal rats in D-VARA and M-VA groups as predicted by the plasma-view model
Treatment Group | |||
Parametersa | Oil | D-VARA | M-VA |
t(5), h | 0.40 | 0.24 | 0.26 |
t(6), days | 1.64 | 1.14 | 1.03 |
T(5,5), days | 2.40 | 0.18 | 0.06 |
FCR(5,5), day−1 | 0.42 | 5.56 | 16.7 |
FCR(5,5), day−1 (after day 8) | 14.7 | 5.56 | 16.7 |
ν(5) | 144 | 17 | 5 |
Parameters shown are: mean transit time [t(5)], or the mean of the time that a retinol molecule spends in compartment 5 (plasma retinol-RBP) during a single transit before leaving reversibly or irreversibly; mean transit time [t(6)], or the mean of the time that a retinol molecule spends in compartment 6 (extravascular tissue retinol) during a single transit before leaving reversibly or irreversibly; mean residence time [T(5,5)], or the average of the distribution of times that a molecule of retinol spends in compartment 5 (plasma retinol-RBP) before it leaves irreversibly; FCR(5,5), or the fraction of the plasma retinol pool that is utilized each day; recycling number [ν(5)], or the average number of times a retinol molecule recycles through compartment 5 (plasma retinol-RBP) before it irreversibly exits from it.