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. 2016 Aug;57(8):1455–1464. doi: 10.1194/jlr.M067488

TABLE 1.

Basal parameters and plasma and hepatic total cholesterol after 2 weeks of statin treatment

Control Rosuvastatin Atorvastatin Lovastatin
BW (g) 26.9 (25.5–28.4) 26.7 (26.1–27.1) 25.6 (24.7–26.1) 24.4 (23.5–25.1)a
Food intake (g/day) 4.3 (3.7–5.0) 4.3 (3.6–4.8) 5.4 (4.4–6.5) 4.1 (3.7–4.6)
Fecal output (g/day) 0.77 (0.73–0.83) 0.85 (0.81–0.85) 0.79 (0.65–0.89) 0.60 (0.52–0.75)a
Liver weight (% of BW) 4.6 (3.6–5.0) 4.9 (4.6–5.0) 4.4 (4.4–4.9) 5.1 (5.0–5.6)a
Plasma total cholesterol (mM) 2.32 (2.03–2.49) 2.00 (1.86–2.26) 1.72 (1.38–1.93)a 1.81 (1.64–1.95)a
Hepatic total cholesterol (nmol/mg protein) 29.7 (28.1–31.0) 29.2 (26.9–31.2) 31.5 (28.3–34.0) 38.5 (34.8–41.0)a

Values are expressed as median with the interquartile range.

a

P < 0.05 versus control.

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