Table 1.
Prediction output and performance of HeLa organellar maps. The table shows the combined organellar prediction output from six replicate maps from HeLa cells. Prediction performance is judged by the proportion of correctly assigned organellar marker proteins. Please also refer to Supplementary file 1 (compact format) and 4 (complete database), which contain detailed information for all 8710 proteins covered in this study, including nuclear and cytosolic predictions. Supplementary file 2 shows the performance of each individual map.
| Compartment | Number of marker proteins | Correctly predicted markers |
All proteins predicted in this compartment | |
|---|---|---|---|---|
| Number | % | |||
| Endosome | 85 | 75 | 88.2% | 304 |
| ER | 127 | 127 | 100.0% | 530 |
| ER, high curvature | 11 | 11 | 100.0% | 45 |
| ERGIC/cisGolgi | 26 | 25 | 96.2% | 73 |
| Golgi | 33 | 29 | 87.9% | 190 |
| Lysosome | 43 | 41 | 95.3% | 88 |
| Mitochondrion | 242 | 239 | 98.8% | 658 |
| Peroxisome | 21 | 15 | 71.4% | 25 |
| Plasma membrane | 127 | 123 | 96.9% | 510 |
| All organellar proteins | 715 | 685 | 95.8% | 2423 |
| Average per organelle | 92.7% | |||
| Large Protein Complexes | 361 | 353 | 97.8% | 2739 |
| Total | 1076 | 1038 | 96.5% | 5162 |