Skip to main content
. Author manuscript; available in PMC: 2016 Jul 25.
Published in final edited form as: Cell Stem Cell. 2010 Sep 3;7(3):299–313. doi: 10.1016/j.stem.2010.08.002

Figure 1. Diversity of PRC1 and PRC2 Complexes Formed by Vertebrate PcG Proteins.

Figure 1

Subunits of the PRC1 (right panel) and PRC2 (left panel) complexes are indicated. The Drosophila homolog of each subunit is indicated in light blue. Multiple combinations of paralog subunits can generate a diversity of PRC1 and PRC2 complexes, which likely have specific and shared functions. Some subunits seem to be present in substoichiometric amounts and interact with the PcG complexes in a cell-context-dependent manner. The core subunits and the substoichiometric subunits are identified. The contacts illustrated in the diagrams are not intended to represent the actual interactions. Involvement of EPC and ASXL subunits with PRC2 or PRC1 complexes is still unclear and requires further investigations.