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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Ann Rheum Dis. 2016 Jan 25;75(11):2014–2021. doi: 10.1136/annrheumdis-2015-208140

Figure 1.

Figure 1

IFN-α reporter activity levels increase as individuals move toward SLE classification. Increases in serum IFN-α activity score by time before SLE classification (A) and by autoantibody status (B) are shown (mean ± SEM). IFN-α activity score ≥ 1 is considered positive (dashed line). Percent of case samples positive for IFN-α activity is listed below each time point. *p<0.05, ***p<0.001, Kruskal-Wallis with Dunn’s multiple comparison. Demographics (C) and number of positive autoantibodies (D, mean ± SEM; *p<0.05, unpaired t-test) in SLE cases that are ever IFN-α activity positive vs SLE cases that remain IFN-α activity negative are also shown. Other = Asian/Pacific Islander, American Indian/Alaskan Native, or multiracial