Table 2.
Pulmonary Exacerbations: Clinical Characteristics
| Characteristic | Total (N=73)a | Mild (N=41)a | Moderate/Severe (N=32)a |
|||
|---|---|---|---|---|---|---|
| Male b | 16 | (47) | 11 | (68.75) | 5 | (27.78) |
|
Age at baseline (years; median, interquartile range) |
11.46 | (7.53, 14.70) |
8.81 | (6.98, 12.94) |
13.08 | (10.55, 15.66) |
|
BMI percentile at baseline
(median, interquartile range) |
44 | (28, 83) | 51 | (28.5, 75.5) |
39 | (24, 87) |
|
Loss in FEV1 % predicted
from baseline (median, interquartile range) c |
7 | (2, 15) | 7 | (1, 13) | 10 | (4, 17) |
| Severity | ||||||
| Mild | 41 | (56.16) | 41 | (100.00) | ||
| Moderate | 27 | (36.99) | 27 | (84.38) | ||
| Severe | 5 | (6.85) | 5 | (15.62) | ||
| Symptoms | ||||||
| Cough | 71 | (97.26) | 40 | (97.56) | 31 | (96.88) |
| Fatigue | 48 | (65.75) | 23 | (56.10) | 25 | (78.13) |
| Fever | 9 | (12.33) | 2 | (4.88) | 7 | (21.88) |
| Weight loss | 35 | (47.95) | 13 | (31.71) | 22 | (68.75) |
| Shortness of breath | 10 | (13.70) | 2 | (4.88) | 8 | (25.00) |
| Crackles | 29 | (39.73) | 8 | (19.51) | 21 | (65.63) |
| Wheeze | 2 | (2.74) | 0 | (0.00) | 2 | (6.25) |
a
: Results represented as n(%) unless otherwise indicated.
b
: For 34 subjects (16 male, 18 female), there were 73 exacerbations; 16 subjects had only mild exacerbations and 18 subjects had at least one moderate/severe exacerbation.
c
: 70 exacerbations had information on FEV1.