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. Author manuscript; available in PMC: 2016 Sep 7.
Published in final edited form as: Biometrics. 2016 Jan 26;72(3):926–935. doi: 10.1111/biom.12475

Table 2.

Power (%), Scenario 1: Uncensored data, 4 outcomes, θϕ= (.03,.08,.16,.28). n, m = sample size per strata in each group, respectively. TO = O'Brien original test; TOU=Proposed O'Brien test; TOU,Ad=Proposed Adaptive O'Brien test; TOU,Opt=Optimal O'Brien Test. wopt = Optimal weight vector. ρ = correlation between outcomes.

ρ No. Strata n m TO
TOU
TOU,Ad
TOU,Opt
wopt
0 2 20 20 55.6 54.1 52.6 71.6 (.053, .136, .281, .530)
40 40 84.5 84.2 84.8 95.6
4 10 10 55.5 56.7 53.2 74.3
20 20 85.5 85.7 83.9 95.7
0.2 2 30 30 54.5 53.7 59.4 80.1 (0, .024, .276, .700)
60 60 84.1 83.8 90.4 98.2
4 15 15 53.7 54.4 61.3 82.7
30 30 84.2 84.4 90.7 98.3
0.5 2 30 30 38.7 37.7 52.6 77.0 (0, 0, .094, .906)
60 60 66.4 66.1 84.2 96.8
4 15 15 39.4 39.7 56.5 77.9
30 30 66.6 66.5 86.5 96.9
0.8 2 30 30 30.8 30.2 50.1 75.8 (0, 0, 0, 1)
60 60 53.2 52.8 79.6 97.4
4 15 15 30.7 30.9 57.0 78.2
30 30 52.6 52.9 84.2 97.0