Table 3.
Pathway costs
| Number | Pathway description | Pathway cost |
|---|---|---|
| Affected patient pathways | ||
| 1 | Affected individual, BRCA mutation identified | £5606.16 |
| 2 | Affected individual, known familial BRCA mutation identified | £5174.16 |
| 3 | Affected individual, known familial BRCA mutation not identified | £739.88 |
| 4 | Affected individual, declined BRCA testing, higher risk family history | £960.59 |
| 5 | Affected individual, declined BRCA testing, moderate risk family history | £911.08 |
| 6a | Affected individual, BRCA testing negative, higher risk family history | £1630.96 |
| 7 | Affected individual, BRCA testing negative, moderate risk family history | £1581.45 |
| 8 | Affected individual, not eligible for BRCA testing, population surveillance | £501.51 |
| 9 | Affected individual, not eligible for BRCA testing, moderate risk family history | £911.08 |
| 10 | Affected individual, not eligible for BRCA testing, higher risk family history | £960.59 |
| Unaffected patient pathways | ||
| 11 | Unaffected individual, known familial BRCA mutation identified | £7944.56 |
| 12 | Unaffected individual, known familial BRCA mutation, test declined | £835.59 |
| 13 | Unaffected individual, known familial BRCA mutation not identified | £614.88 |
| 14 | Unaffected individual, no testing recommended, higher risk family history | £835.59 |
| 15 | Unaffected individual, no testing recommended, moderate risk family history | £786.08 |
| 16 | Unaffected individual, no testing recommended, population risk | £376.51 |
| 17 | Unaffected individual, affected relative eligible for BRCA testing, mutation identified in affected relative and in individual | £13,553.10 |
| 18 | Unaffected individual, affected relative eligible for BRCA testing, mutation identified in affected relative but not in individual | £6223.42 |
| 19 | Unaffected individual, affected relative eligible for BRCA testing, no mutation identified in affected relative, higher risk family history | £2707.29 |
| 20 | Unaffected individual, affected relative eligible for BRCA testing, no mutation identified, moderate risk family history | £2608.27 |
| 21 | Unaffected individual, affected relative eligible for BRCA testing, no mutation identified in relative, population risk | £1789.13 |
| 22 | Unaffected individual, family eligible for BRCA testing, no relative available or relative does not get tested, higher risk family history | £835.59 |
| 23 | Unaffected individual, family eligible for BRCA testing, no relative available or relative does not get tested, moderate risk family history | £786.08 |
| 24 | Unaffected individual, family eligible for BRCA testing, no relative available or relative does not get tested, population risk | £376.51 |
| 25 | Unaffected individual, known familial BRCA mutation, relative to be tested first, relative negative | £1118.76 |
| 26 | Unaffected individual, family already tested, no mutation identified, moderate risk family history | £786.08 |
| 27 | Unaffected individual, family already tested, no mutation identified, higher risk family history | £835.59 |
| 28 | Unaffected individual, family already tested, no mutation identified, population risk | £376.51 |
aSee Table 2 for details of this pathway