Table 1. Non-invasive study.
Modality/marker | First author | Outcome description | Composite | No. of total events | All cause death | Cardiac death | Cardiac arrest | MI (STEMI/NSTEMI) | UAP | SAP | Coronary revascularization | Duration of follow-up |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CT | ||||||||||||
CAC score | Yeboah | Coronary heart disease | ○ | 104 | × | ○ | ○ | ○ | Δ | ○ | 7.6 yr* | |
Detrano | Coronary heart disease | ○ | 162 | × | ○ | × | ○ | ○ | ○ | 3.9 yr* | ||
Erbel | Non-fatal MI + cardiac death | ○ | 93 | × | ○ | × | ○ | × | × | × | 5 yr* | |
Russo | Hard cardiac events | ○ | 44 | × | ○ | × | ○ | ○ | × | × | 34.8 mon** | |
Elias-Smale | Coronary heart disease | ○ | 135 | × | ○ | × | ○ | × | × | × | 9.2 yr* | |
CTCA (Luminal narrowing) | Min 2007 | All-cause death | × | 39 | ○ | × | × | × | × | × | × | 15.3 mon** |
Hadamitzky 2011 | Cardiac events | ○ | 47 | × | ○ | × | ○ | ○ | × | ○ | 28 mon* | |
Hadamitzky 2013 | All-cause death | × | 347 | ○ | × | × | × | × | × | × | 2.3 yr* | |
Plank | MACE | ○ | 6 | × | ○ | × | ○ | × | × | × | 2.65 yr** | |
Hou | MACE + hard MACE | ○ | 363 | × | ○ | × | ○ | × | × | ○ | 1,081 day* | |
Andreini | MACE + hard MACE | ○ | 259 | × | ○ | × | ○ | × | × | ○ | 52 mon** | |
Min 2014 | MACE | ○ | 33 | ○ | × | × | ○ | × | × | ○ | 2.4 yr** | |
Schlett | MACE | ○ | 35 | × | ○ | × | ○ | × | × | ○ | 2 yr* | |
Total plaque burden | Versteylen | ACS | × | 25 | × | × | × | ○ (ACS) | × | × | 26 mon** | |
PR, LAP and Napkin ring sign | Otsuka | Cardiac death or ACS event | ○ | 24 | × | ○ | × | ○ | ○ | × | × | 3 yr* |
CMR | ||||||||||||
MR coronary angiographic stenosis | Yoon | Combined cardiac endpoints | ○ | 13 | × | ○ | × | × | ○ | × | ○ | 25 mon* |
Coronary high-intensity plaque | Noguchi | Combined endpoints | ○ | 55 | × | ○ | × | ○ | ○ | × | ○ | 55 mon |
Note: “○” means used as a component of composite endpoints and “×” does not used. “Ä” means that it has been reported but included in coronary revascularization. *, median; **, average; MI, myocardial infarction; UAP, unstable angina; SAP, stable angina; CT, computed tomography; CMR, cardiac magnetic resonance imaging; CAC, coronary artery calcium; CTCA, computed tomography coronary angiography; PR, positive remodeling; LAP, low attenuation plaque; MACE, major adverse cardiovascular event; ACS, acute coronary syndrome.